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RE: st: Conditional logistic regression


From   "Gareth Davies (Public Health Wales)" <[email protected]>
To   "[email protected]" <[email protected]>
Subject   RE: st: Conditional logistic regression
Date   Tue, 12 Nov 2013 09:31:43 +0000

Thanks Steve, that is very helpful and that reference looks like essential reading.


-----Original Message-----
From: [email protected] [mailto:[email protected]] On Behalf Of Steve Samuels
Sent: 11 November 2013 22:36
To: [email protected]
Subject: Re: st: Conditional logistic regression


I believe this kind of design is called the "single-subject", "case-time", or "case-crossover" design, the former in the social sciences, the latter in epidemiology. I've never done one, but a Google Scholar search should lead you to references. Off-hand, I see no technical problem with conditional logistic approach per se. However because, in your study, the change goes in only one direction, the effect of pollution will be confounded with temporal trends.

A possibly useful reference, which I haven't read:
Maclure, M., and and M. A. Mittleman. 2000. Should We Use a Case-Crossover Design? Annual Review of Public Health Annu. Rev. Public.
Health. 21, no. 1: 193-221.


Steve
[email protected]



On Nov 11, 2013, at 7:43 AM, Gareth Davies (Public Health Wales) wrote:

Dear all

We have some data on all the individuals in a population for two periods: a period during which an environmental pollution event occurred and the same period the previous year when no pollution event occurred.

For this population we know whether the individuals had a health care event, such as an emergency hospital admission, during either period.

We also know other characteristics such as age, and pre-existing co morbidity.

We want to establish whether the pollution event had any effect on the health care events.

Would it be correct to use conditional logistic regression (clogit) to analyse these data on the basis that they are akin to 'matched case-control' data?

Many thanks

Gareth

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