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st: Interaction term in repeated measures ANOVA or mixed model

From   "Roberts, Matthew (BHH)" <>
To   "''" <>
Subject   st: Interaction term in repeated measures ANOVA or mixed model
Date   Thu, 3 Oct 2013 05:15:10 +0000

I have Stata/IC 11.2 for Mac

In my dataset, I have a continuous variable logntbnp measured on ~240 individual patients (id) on two occasions (visit=1 and visit=2).

I wanted to test if the change over time in logntbnp between visit=1 and visit=2 was different between 3 groups of patients (modality=0, modality=1, modality=2).

With data in long format, I ran:

anova logntbnp modality / id|modality visit modality#visit, repeated(visit)

The p for modality#visit was significant and I concluded that the change in variable logntbnp over time (visit) was significantly different among 3 groups of patients (modality).  The visit term was also significant.

It has been suggested that this difference might be due to differences between groups, i.e. age, diabetes etc.

Is the command below the way to set up a model that looks at this interaction and adjusts for the effect of age in anova?

anova logntbnp modality / id|modality visit modality#visit c.age, repeated(visit)

Would I be better off using xtmixed to do this?  How would this work to test the interaction?

Dr Matthew Roberts


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