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From | Xin Lu <xinlu2004@gmail.com> |
To | statalist@hsphsun2.harvard.edu |
Subject | Re: st: test for homogeneous odds ratios in D+L random effects model |
Date | Thu, 30 Sep 2010 10:27:31 -0500 |
The dependent variable in meta-regression would be the ln(OR), that is, the pre-post variable is embedded in it already. The interaction I would like to test is how the "pre-post" interacts with the "vendor affiliation", and try to answer the question "whether vendor affiliated studies would have a bigger impact on reducing mortality in the "post" comparing to "pre" ". Thanks, On Thu, Sep 30, 2010 at 3:05 AM, Jonathan Sterne <Jonathan.Sterne@bristol.ac.uk> wrote: > Hi - you need meta-regression implemented in the Stata command metareg - I > recommend that you read Roger Harbord's recent article in the Stata Journal. > > Best wishes > > Jonathan Sterne > > --On 30 September 2010 02:33 -0400 statalist-digest > <owner-statalist@hsphsun2.harvard.edu> wrote: > >> Date: Wed, 29 Sep 2010 11:33:55 -0500 >> From: Xin Lu <xinlu2004@gmail.com> >> Subject: st: test for homogeneous odds ratios in D+L random effects model >> >> We are collaborating with some investigators off site on a >> meta-analysis regarding mortality of tele-ICU?implementation (Post >> versus Pre). We are using STATA metan package to conduct D+L random >> effects model to pool the odds ratios of mortality from various >> studies, and also conducting subgroup analysis based on vendor >> affiliation (vendor affiliated versus not vendor affiliated). The >> investigators off site asked us to test for homogeneous odds ratios >> between the two subgroups (vendor affiliated versus not vendor >> affiliated). However, as far as we can find, such test (breslow-day >> test) can only be performed using fixed inverse variance model, which >> differs from the D+L random effects model we are using. They insisted >> there should be a way to do it. We are not expert on meta-analysis, >> and therefore we can't say for sure there is no way to achieve it. >> >> Any insights? >> >> Thanks a million! >> Xin >> > > > > > ---------------------- > > Jonathan Sterne > Professor of Medical Statistics and Epidemiology > School of Social and Community Medicine > University of Bristol > Canynge Hall > 39 Whatley Road > Bristol BS8 2PS > UK > > Tel: 0117 928 7396 > Fax: 0117 928 7325 > E-mail: jonathan.sterne@bristol.ac.uk > web: www.epi.bris.ac.uk/staff/jsterne.htm > > * > * For searches and help try: > * http://www.stata.com/help.cgi?search > * http://www.stata.com/support/statalist/faq > * http://www.ats.ucla.edu/stat/stata/ > * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/