In our analysis ONE study reported two Zero cell events: 0/n1events in the intervention group and 0/n2 events in the treatment group;
*The study is either excluded or creates very large confidence intervals...
Our codes is as follows:
metan t_outcome t_nooutcome c_outcome c_nooutcome, rr fixedi...
Here is what we have tried so far:
1) When we run our usual metan(with both cells as Zero), this study is EXCLUDED
2) When we run our metan and add a continuity correction "cc(0.5)" , the study is excluded.
3) When we manually add 0.5 to the zero cells and use the command "nointeger", the confidence intervals span from 0 to 100 and present an unpleasing forest plot.
4) It didnt make a difference if we used inverse variance (fixedi) or Mantel and Haenszel (fixed)...
Most of the solutions I have found by searching seem to be if you have one zero cell;
We want to have this particular outcome be a figure in our manuscript, so it is important that the forest plot be displayed correctly.
Any guidance on suggestions/references for how to handle this would be greatly appreciated.
Thanks
Elliott
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