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Re: st: ttest or xtmelogit?

From   David Airey <david.airey@Vanderbilt.Edu>
Subject   Re: st: ttest or xtmelogit?
Date   Mon, 10 Mar 2008 16:49:13 -0500


Maybe I should not have said it was pilot data! I won't disagree, but when cluster number is too small (< 20) to invoke xtgee or xtmelogit on the observed yes/no data, or glm on the summary statistics with binomial family and logit link, what do you do? It seems to me there is a sample size between 10 and 30 clusters of yes/no data that may be better suited to some of the older approaches like arcsin transformed proportions and then ttest or ANOVA/regress. I guess that was my question.

On Mar 10, 2008, at 4:30 PM, wrote:

modelling error structure with a pilot study in pharmacology sounds funny,
specially with 6 mice in each group, Nick. Math and statistics sometimes
blind researchers.

I would not try to answer anything with a pilot study (in
pharmacology/biochemistry, etc..).

Pilots are done to see the direction of the effect. If it shows a signal,
we keep going. If not, we stop and try other alternatives. Mann- whitney
sounds ok, at least in my modest view.


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