Re: st: ttest or xtmelogit?

[David Airey <david.airey@Vanderbilt.Edu>]

.

Maybe I should not have said it was pilot data! I won't disagree, but  
when cluster number is too small (< 20) to invoke xtgee or xtmelogit  
on the observed yes/no data, or glm on the summary statistics with  
binomial family and logit link, what do you do? It seems to me there  
is a sample size between 10 and 30 clusters of yes/no data that may be  
better suited to some of the older approaches like arcsin transformed  
proportions and then ttest or ANOVA/regress. I guess that was my  
question.


On Mar 10, 2008, at 4:30 PM, tiago.pereira@incor.usp.br wrote:


> modelling error structure with a pilot study in pharmacology sounds  
> funny,
> specially with 6 mice in each group, Nick. Math and statistics  
> sometimes
> blind researchers.
>
> I would not try to answer anything with a pilot study (in
> pharmacology/biochemistry, etc..).
>
> Pilots are done to see the direction of the effect. If it shows a  
> signal,
> we keep going. If not, we stop and try other alternatives. Mann- 
> whitney
> sounds ok, at least in my modest view.
>
>
>
> Tiago
>
>
>
>
>
>
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