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Re: st: Split Population Survival (Cure) Model with discrete timedata

From   "E. Paul Wileyto" <>
Subject   Re: st: Split Population Survival (Cure) Model with discrete timedata
Date   Wed, 19 Dec 2007 07:12:27 -0500

Look in The Stata Journal (2007), Vol. 7, Number 3, pp. 351-375 for an article on cure models by Paul Lambert.

You can retrieve Lambert's set of routines by searching for -strsmix- from Stata Help. It's a very flexible set of parametric cure models.


Javier Sesé wrote:

Dear all,

I am trying to estimate a Split Population Survival Model (also called
Cure Model) with discrete time duration data in Stata 9.0. This model
relaxes the assumption that all subjects will eventually experience
the event of interest by supposing that a proportion of the population
never fail.

The -spsurv- Stata module developed by Stephen P. Jenkins estimates
this model, but it assumes that the cure probability (the probability
of a subject never failing) is common to all individuals. The code can
be found at:

However, I am interested in running a Split Population Survival Model
that allows for differences between individuals in this probability,
for instance, by using a logistic relationship between some
explanatory variables and the cure probability. But I have no clue
about how to do this in Stata, or how to modify the original code of
the -spsurv- module to incorporate this heterogeneity in the cure

If it helps, Forster, M. and Jones, A.M. (2001) ("The
role of tobacco taxes in starting and quitting smoking: duration
analysis of British data" Journal of the Royal Statistical Society A,
164(3), pp.517-547) have developed a Stata code to estimate this model
for continuous time data (the code can be found at

Any help would be much appreciated.
Thank you in advance

* For searches and help try:

E. Paul Wileyto, Ph.D.
Assistant Professor of Biostatistics
Tobacco Use Research Center
School of Medicine, U. of Pennsylvania
3535 Market Street, Suite 4100
Philadelphia, PA 19104-3309

Fax: 215-746-7140
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