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Re: st: RE: RE: Spaghetti Plots

From   Ronan Conroy <>
To   "" <>
Subject   Re: st: RE: RE: Spaghetti Plots
Date   Wed, 8 Sep 2010 13:10:18 +0100

On 3 MFómh 2010, at 18:20, Lachenbruch, Peter wrote:

What's also mildly amusing is that there's an outstanding pharmacologist named Louis Lasagna - no relation to spaghetti or any other plots that I know of.

He also propounded one of the more amusing laws of research:

L: Lasagna's Law

It was one of the pioneers in clinical pharmacology, the American Louis Lasagna, who described in 1970 a today's still well-known phenomenon in clinical trials: The incidence of patient availability sharply decreases when a clinical trial begins and returns to its original level as soon as the trial is completed. For illustration, in 1979 Lasagna commented on a trial where out of 8,000 patients theoretically available just 100 patients in the end participated. Later this phenomenon was popurlarly called Lasagna's Law.

From The A-Z of Pharmaceutical Medicine, PFC Pharma Focus AG, Chriesbaumstrasse 2, CH-8604 Volketswil

Ronán Conroy
Associate Professor
Division of Population Health Sciences
Royal College of Surgeons in Ireland
Epidemiology Department,
Beaux Lane House, Dublin 2, Ireland
+353 (0)1 402 2431
+353 (0)87 799 97 95
+353 (0)1 402 2764 (Fax - remember them?)

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