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st: Trend test in meta analysis


From   "Jayaprakash, Vijay" <Vijay.Jayaprakash@roswellpark.org>
To   <statalist@hsphsun2.harvard.edu>
Subject   st: Trend test in meta analysis
Date   Fri, 21 Dec 2007 15:52:47 -0500

Hi Stata users,
       I'm trying to do a meta analysis of data from 10 different studies. The smoking variable in each study is stratified into categories (Category 1:1-10 cigarettes, Category 2: 10-20 cigs, Category3: 20-30 cigs etc.). I calculated the OR for each category (of smoking) by study.  I then did a meta analysis and calculated the OR for each category by random effects model using the meta command: 
meta  or1 lcl1 ucl1, ci eform 
meta  or2 lcl2 ucl2, ci eform 

I found that metap command can provide the p-value for each category (from p-values of each study for that specific category). Is there a way to get the p for trend BETWEEN the categories from the random effects estimate? I would like to report from the meta-analysis results if there is a dose-response relationship of smoking to the disease and if so what the p for trend is.

I will very much appreciate your help.

Thanks

Vijay

 


 


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