Dear All,
I have been using
PKSHAPE to reshape data for a 3X3 crossover trial.
I have data
originally arranged by period for the 6 periods of the trial (i.e. 1=baseline,
2=period 2, 3=1st wash-out, etc.)
I have seq (variable
for sequence) coded as string of the type '0a0b0c'
I have pk-reshaped
the dataset to obtain a long format dataset in order to be used by the command
PKCROSS.
namely I typed:
pkshape id seq phv1 phv2 phv3 phv4 phv5 phv6,
outcome(phv)
I have saved the
results in a new dataset and repeated the same command for another outcome
(phn); saved results in another dataset as well.
I have then merged
together the two datasets matching by id and sequence.
I have therefore run
the command pkcross on each outcome variable separately and everything seemed to
work fine (the PKCROSS output is straightforward).
Nonetheless
when I tried to calculate the averages and standard deviations for each
outcome by treatment (with the command
table), the figures appear incorrect!
I have checked this
with the averages on the outcome variable by period, sequence and in such
instance the problem doesn't occur: the estimates are
corrrect!
Has anyone else
experienced the same problem?
Any help would be
highly appreciated,
Regards,
Roberto.
***********************************
Roberto
Melotti, Senior Statistician
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