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st: Meta-analysis of diagnostic tests


From   "Seligman, Hilary" <hseligman@medsfgh.ucsf.edu>
To   statalist@hsphsun2.harvard.edu
Subject   st: Meta-analysis of diagnostic tests
Date   Tue, 21 Mar 2006 11:24:55 -0800

Has anybody used Stata to do a meta-analysis of diagnostic tests?
Specifically, I would like to generate summary positive and negative
likelihood ratios with p-values, and an associated test of
heterogeneity. 
I am not convinced that the metan command (metan tp fn fp tn, with
tp=true positive, fn=false negative, etc.), as some have suggested,
produces correct results.  

As a (less desirable) alternative, I believe that I can use a logit
command to generate a summary sensitivity/specificity.  However, I am
unclear on how that would actually be coded.  

Any advice on either approach would be MUCH appreciated.

Thanks very much,

Hilary Seligman
hseligman@medsfgh.ucsf.edu




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