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st: When is 'no trimming' performed using metatrim


From   Setor Kunutsor <skk31@medschl.cam.ac.uk>
To   "statalist@hsphsun2.harvard.edu" <statalist@hsphsun2.harvard.edu>
Subject   st: When is 'no trimming' performed using metatrim
Date   Sun, 24 Feb 2013 13:58:17 +0000

Hi all,

I have conducted a meta-analysis based on a total of 10 studies using a Random-effects model. There was substantial heterogeneity among contributing studies (I2>70%).

 A funnel plot revealed evidence of publication bias which was further confirmed by Egger’s regression symmetry test (P=0.03).

I am using the trim-and-fill method to adjust for publication bias. I am aware this method performs poorly in the presence of substantial between study heterogeneity.

On running the metatrim command, the output suggests that no trimming was performed.

What does this mean? Does it mean there was no publication bias? How do I interpret the results?

Many thanks

S. Kunutsor


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