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From |
"Kieran McCaul" <kamccaul@meddent.uwa.edu.au> |

To |
<statalist@hsphsun2.harvard.edu> |

Subject |
RE: st: RE: FWD: poisson regression on aggrgregated data |

Date |
Tue, 10 Feb 2009 06:28:51 +0900 |

OK, I see. You have the year that treatment started: 1997,1998,1999,...,2008 which you have coded as: year_start_cat = 1 if year_start=1997 and year_start_cat = 2 if year_start=1998,1999,...,2008 You have time since the treatment started (time_since_start):0_1, 1_2, 2_3,...,Max coded as: time_since_start_cat = 1 if time_since start = 0_1 . time_since_start_cat = 2 if time_since start = 1_2 time_since_start_cat = 3 if time_since start = 2_3,...,Max Then you modelled the incidence rates using these covariates and now you want to predict the rates in each of the calendar years that treatment started (1997,1998,1999,...,2008) and in each of the years since treatment started (0_1, 1_2, 2_3,...,Max). Your model is assuming that the rate in the treatment years 1998 to 2008 is the same. Similarly, it is assuming that after two years of follow-up have elapsed, the rate is the same; constant with time since treatment started. In fact, it is assuming that this constant rate is the same for all treatment years, 1998 to 2008. If these assumptions are correct, then you could use the model to predict the rates, but you would need to provide some evidence that they are correct. If you have sufficient data, you could use -strate- to generate the rates for year_start and time_since start to see if your assumptions are essentially correct. strate year_start time_since start This would give you the annual incidence rates since treatment started and you could graph these for each calendar year. I did something similar to this in a study of second primary melanoma rates: McCaul et al. The incidence of second primary invasive melanoma in Queensland, 1982-2003. Cancer Causes Control 2008; 19(5):451-8. Alternately, you could go back to your original data and use Kaplan-Meier to generate hazard curves by calendar year of treatment. These should be constant three or more years after treatment and they should be similar for 1998 through to 2008. ______________________________________________ Kieran McCaul MPH PhD WA Centre for Health & Ageing (M573) University of Western Australia Level 6, Ainslie House 48 Murray St Perth 6000 Phone: (08) 9224-2140 Fax: (08) 9224 8009 email: kamccaul@meddent.uwa.edu.au http://myprofile.cos.com/mccaul http://www.researcherid.com/rid/B-8751-2008 ______________________________________________ The fact that no one understands you doesn't make you an artist. -----Original Message----- From: owner-statalist@hsphsun2.harvard.edu [mailto:owner-statalist@hsphsun2.harvard.edu] On Behalf Of [Redacted] Sent: Monday, 9 February 2009 9:30 PM To: statalist@hsphsun2.harvard.edu Subject: RE: st: RE: FWD: poisson regression on aggrgregated data Dear Kieran No I am not modeling mortality rates, I am modeling the incident of experiencing an event by patients using these 2 covariates: year_start (year of starting treatment): 1997,1998,1999,...,2008 time_since_start:0_1, 1_2, 2_3,...,Max My original data was not in aggregated form, and patients experienced the event (1) or not (0). Then I splitted the follow up time in one year periods and coded year_start,1997 as 1 and 1998+ as 2 and time_since start ,0_1 as 1, 1_2 as 2 and 2+ as 3. then aggregated data using these coded covariates: strate year_start_cat time_since_start_cat saved the output, and used poisson on _D (count of events in each group)-created by strate-, above 2 coded covariates (year_startcat, time_since_startcat) and the exposure that would be created aggregated follow up time _Y ,and then predicted number of events and incident rates in each group using predict. Now I would like to use the coefficients of this fitted poisson model and have the predicted incident rates in disaggregated data (for year_start and time_since_start before grouping them) for example the incident rate for year_start=2003 (whitch has been coded as year_startcat=2) and year_since_start=3_4 (which has been coded as year__since_startcat=3) Would it be correct if I use the same predicted incident rate from poisson on grouped data (1998+ and 2+) and use it for above example or each case in this group or in this case more events than really is will be predicted? Many thanks, Shell > Subject: st: RE: FWD: poisson regression on aggrgregated data > Date: Mon, 9 Feb 2009 04:09:31 +0900 > From: kamccaul@meddent.uwa.edu.au > To: statalist@hsphsun2.harvard.edu > > . > > It's not clear from this description what you are modelling. Is it > mortality rates? > Second, when you say that you have used aggregated data, is this data > that you have aggregated or was the data already in aggregated form? > > > > ______________________________________________ > Kieran McCaul MPH PhD > WA Centre for Health & Ageing (M573) > University of Western Australia > Level 6, Ainslie House > 48 Murray St > Perth 6000 > Phone: (08) 9224-2140 > Fax: (08) 9224 8009 > email: kamccaul@meddent.uwa.edu.au > http://myprofile.cos.com/mccaul > http://www.researcherid.com/rid/B-8751-2008 > ______________________________________________ > The fact that no one understands you doesn't make you an artist. > > -----Original Message----- > From: owner-statalist@hsphsun2.harvard.edu > [mailto:owner-statalist@hsphsun2.harvard.edu] On Behalf Of Martin Weiss > Sent: Sunday, 8 February 2009 7:55 PM > To: statalist@hsphsun2.harvard.edu > Subject: st: FWD: poisson regression on aggrgregated data > > <> > > Dear [Redacted], > > short answer: I do not know! BTW, it is not clear to me why you want to > tap > only my wisdom when you can have the entire list. So I am forwarding > this > topic to the list for you... > > > HTH > Martin > _______________________ > > > Dear Martin > > I would like to ask the following question. > > I have used poisson regression on aggrgregated data with 2 covariates > (in a > cohort of HIV positive patients) > > 1.year of starting 3+ antiretroviral treatment (1997, 1998+) > 2.time since starting 3+antiretrovirals (0-1, 1-2, 2+) > > and I have predicted incident rates in this aggregated data using > predict > option after the poisson model. > > Now my question is if I want to have predicted incident rates for > patients > starting 3+ arvs at 2000 and time since starting 3+ arvs , 3_4 years > is it correct to use the same predicted incident rate obtained for > aggregated data and in this example use predicted incident rate for > 1998+ > and 2+? > > It would be greatly appreciated if you could answer my question, Please > let > me know if you would like me to provide more details. > > Thank you very much in advance, > > Kind regards, > Shell > > * > * For searches and help try: > * http://www.stata.com/help.cgi?search > * http://www.stata.com/support/statalist/faq > * http://www.ats.ucla.edu/stat/stata/ > > > > * > * For searches and help try: > * http://www.stata.com/help.cgi?search > * http://www.stata.com/support/statalist/faq > * http://www.ats.ucla.edu/stat/stata/ _________________________________________________________________ News, entertainment and everything you care about at Live.com. Get it now! http://www.live.com/getstarted.aspx * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/ * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/

**Follow-Ups**:**RE: st: RE: FWD: poisson regression on aggrgregated data***From:*[Redacted]

**RE: st: RE: FWD: poisson regression on aggrgregated data***From:*[Redacted]

**References**:**st: FWD: poisson regression on aggrgregated data***From:*"Martin Weiss" <martin.weiss1@gmx.de>

**st: RE: FWD: poisson regression on aggrgregated data***From:*"Kieran McCaul" <kamccaul@meddent.uwa.edu.au>

**RE: st: RE: FWD: poisson regression on aggrgregated data***From:*[Redacted]

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