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Re: st: Analysis of longitudinal data from medical records

From   Fred Wolfe <>
Subject   Re: st: Analysis of longitudinal data from medical records
Date   Thu, 01 Sep 2005 09:44:21 -0500

There is no simple approach to medication issues in medical records in observational studies. Treatment data are often left and right censored, altered by dose adjustment and concomitant medications. Much depends on the goals of the analysis, the assumptions you are making, and the quality and amount of data. Standard data principles apply and you have to take it a step at a time. Mixed models do not alter these other concerns.

Fred Wolfe
National Data Bank for Rheumatic Diseases

At 09:22 AM 9/1/2005, you wrote:

Can anyone recommend a good paper or text covering the
analysis of repeated measures data from medical
charts/electronic medical records?  I am working on a
project using data from an EMR and am not sure if
there is a conventional approach to handling issues
like medication discontinuation and switching.  I have
a text entitled "Applied Mixed Models in Medicine" by
H. Brown & R. Prescott that has been of some help.
Any other suggestions would be appreciated.


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