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st: equivalence trial power calculation

From   "Jannik Helweg-Larsen" <[email protected]>
To   <[email protected]>
Subject   st: equivalence trial power calculation
Date   Tue, 7 Oct 2003 22:38:07 +0200

Dear list

Using Stata 8.1

I'm unsure on how to calculate the required sample for the following trial,
been searching by findit for equivalence ado's without finding my answer:

We are planning to do a 2 year equivalence trial.The current standard of
treatment has a 2 year failure rate of 7%: In our trial of a new drug, the
treatments will be considered equivalent if the 95% confidence interval are
within the bound of -12% to 12%, which we believe is the  the largest
difference that would be considered clinically acceptable.

any suggestions?

Jannik Helweg-Larsen

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