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st: new package -extfunnel- available on SSC


From   "Crowther, Michael J." <mjc76@leicester.ac.uk>
To   "statalist@hsphsun2.harvard.edu" <statalist@hsphsun2.harvard.edu>
Subject   st: new package -extfunnel- available on SSC
Date   Mon, 22 Aug 2011 11:57:14 +0100

Thanks to Kit Baum a new package -extfunnel- is now available from SSC. 
 
-extfunnel- creates graphical overlay augmentations to the funnel plot. The purpose of these overlays is to display the potential impact a new study would have on an existing meta-analysis, providing an indication of the robustness of the meta-analysis to the addition of new evidence. Thus, these extend the use of the funnel plot beyond assessments of publication biases. Two main graphical displays can be produced; i) statistical significance contours, which define regions of the funnel plot in which a new study would have to be located in order to change the statistical significance of the meta-analysis; and ii) heterogeneity contours, which show how a new study would affect the extent of heterogeneity in a given meta-analysis. extfunnel can also illustrate the impact a new study has on lower and upper confidence interval values, the confidence interval width of the pooled meta-analytic result, and overlays for the impact of a future study on, user defined, limits of clinic!
 al equivalence. Inverse variance weighted methods are implemented using both explicit formulae for contour lines, and a simulation approach optimised in Mata.
 
Thanks,
Michael


Michael Crowther
Research Assistant in Medical Statistics
Centre for Biostatistics & Genetic Epidemiology
Department of Health Sciences
University of Leicester
Adrian Building
University Road
Leicester LE1 7RH
Tel: 0116 229 7278
E-mail: mjc76@le.ac.uk
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