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help for ^genhwcci^                                               (STB-57: sg150)
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Hardy-Weinberg equilibrium test in case-control studies
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^genhwcci^ #AA1 #Aa1 #aa1 #AA2 #Aa2 #aa2 [^,^ ^l^abel^(^genotypes^)^ ^bin^var]

^fweight^s are allowed; see help @weights@.


Description
-----------

^genhwcci^ is an immediate commmand used for estimating allele frequency, 
genotype frequencies, and disequilibrium coefficients for codominant traits
or data of completely known genotypes in case-control studies. It performs 
asymptotic Hardy-Weinberg equilibrium test for both cases and controls in 
case-control studies. It also tests the Hardy-Weinberg equilibrium for 
genotypic counts of cases, under the assumption that the genotypic counts of 
controls are under Hardy-Weinberg equilibrium; where #AA1, #Aa1 and #aa1 are 
the counts for the AA, Aa and aa genotypes of cases and #AA2, #Aa2 and #aa2 
are the counts of controls. Note that this command only works for biallelic 
loci.


Options
-------

^binvar^ requests that the standard errors from binomial distribution are
reported for each allele frequency. These standard errors are calculated 
assuming that the population is under Hardy-Weinberg equilibrium. By default, 
standard errors that do not require this assumption are reported.

^label^ specifies labels to be used in the output of the genotype frequency
table. 


Examples
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 . ^genhwcci 67 156 146 31 135 118 , binvar label(AA Aa aa)^
 . ^genhwcci 41 47 21 37 58 18^



Author
------

       Jisheng Cui
       University of Melbourne
       j.cui@@gpph.unimelb.edu.au


Also see
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    STB:  STB-48 sg110
 Manual:  [R] genhw 
On-line:  help for @genhwi@