st: gllamm and u-shaped cumulative logits over time
Date
Tue, 19 Mar 2013 20:17:34 +0000
Dear statalist users,
I am working on a longitudinal dataset dealing with depression, measured
as ordinal variable (1: none, 2: mild, 3:moderate, 4: severe). There are
5 measurement points (t0-t4) and two different groups (T0=conventional
treatment GP, T1=new treatment). I want to find out whether the
treatment has an influence on the development of the depression score. I
would normally use the -gllamm- command with the model (without a random
slope) looking something like this:
gllamm depr week treatment interact, i(id) link(ologit) adapt eform
, where week is the time tx-t0 and interact=week*treatment.
But here is my problem: The development over time (and over time by
group) is not linear but clearly (!) u-shaped. There is a short-term
effect in both groups, i.e. the depression scores decline considerably
from t0 to t1. However, in the long run (t1-t4), the scores in both
groups increase again and often even exceed the initial value at t0. For
obvious reasons, the above model fits the data very poorly.