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st: Cut-off point for ROC curve using parametric and non-parametric method


From   Pham Ngoc Minh <[email protected]>
To   [email protected]
Subject   st: Cut-off point for ROC curve using parametric and non-parametric method
Date   Sat, 19 Jan 2013 12:38:03 +0900

Dear Statalist,

I want to construct age-adjusted (age is a continuous variable) optimal
cut-off points for body mass index (bmi)  and waist circumference (wc) in
determining metabolic syndrome (metabo) for a large study. My question is
how can I calculate sensitivity and specificity for bmi and wc with
adjustment for age, based on which I can calculate Youden index. For
non-parametric method, I know only about using command: roctab metabo bmi,
detail or senspec metabo bmi, se(varname1) spe(varname2)  (without
covariate adjustment). Moreover, how can I calculate age-adjusted
sensitivity and specificity using parametric ROC analysis. It is because
 using non-parametric method showed P less than 0.01, although AUC for
bmi and wc was somewhat similar.
Thank you for your guidance in advance.

Pham Ngoc Minh
Thai Nguyen University Faculty of Public Health, Vietnam
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