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From |
"Turnbull, Alison E." <aturnbul@jhsph.edu> |

To |
"statalist@hsphsun2.harvard.edu" <statalist@hsphsun2.harvard.edu> |

Subject |
st: Using the predictnl command following a model containing restricted cubic splines and time-dependent effects |

Date |
Wed, 3 Oct 2012 22:35:22 -0400 |

Hello, I'm working with a model developed using the stpm2 package from SCC. The baseline hazard has 4 degrees of freedom with knots at time = 3, 7 and 21. Variable x1 is a continuous variable with a time-dependent effect and a knot at time=21. Variables x2 is a dichotomous variable with a time-dependent effect and a knot at time= 21. The 4 derived spline variables for the baseline log cumulative hazard are _rcs1 _rcs2 _rcs3 _rcs4 And the spline variables for the time-dependent effects of x1 and x2 are _rcs_x11 _rcs_x12 and _rcs_x21 _rcs_x22 I would like calculate the hazard ratios and associated 95% CIs for individuals with x1=1 relative to those with x1=0 at time = 2, 7, 10 and 30 as well as the hazard ratios for individuals with varying levels of x2 at the same time points. I realize that these hazard ratios are non-linear functions of the model parameters and will require use of the predictnl command but I am struggling to figure out the right equation. I would be greatly appreciative if someone could write out the command for one of these desired hazard ratios to help get me started. Thank you, alison * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/faqs/resources/statalist-faq/ * http://www.ats.ucla.edu/stat/stata/

**Follow-Ups**:**st: RE: Using the predictnl command following a model containing restricted cubic splines and time-dependent effects***From:*"Lambert, Paul C. (Dr.)" <pl4@leicester.ac.uk>

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