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st: compare small sample size with very large sample size

From   Caliph Omar Moumin <>
To   "" <>
Subject   st: compare small sample size with very large sample size
Date   Fri, 27 Apr 2012 03:28:03 -0700 (PDT)

Cost Comparison:
based on patient admission and treatment duration for non-alcohol related diagnosis.
Alcoholic group                       vs.                               Non alcoholic group
Sample 43 patients                     Vs.                             sample size 21,028 patients
            107observations               Vs.                                               24,204 observations
The data is obtained from a patient registry.
Is it possible  to compare such small sample size with very large group??????????????????? if yes what is stata command should i apply????
..If that is no, which i think it is! How about selecting 50 patients from the non alcoholic group???? will that lead to a bias??
Could anyone please comment?????
Kind Regards,


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