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From |
David Hoaglin <dchoaglin@gmail.com> |

To |
statalist@hsphsun2.harvard.edu |

Subject |
Re: st: Meta-analysis pooling relative risk from relative risks possible? |

Date |
Thu, 16 Feb 2012 07:31:16 -0500 |

Do the relative risks reported by the individual studies come from their respective 2x2 tables, or are they adjusted? If they incorporate adjustments, and the variables used in the adjustments differ among studies, the relative risks are not comparable. Although it is customary to weight the studies' estimates proportional to the reciprocal of the estimated variance, bias can result, even in fixed-effect meta-analysis. The books and software generally give no warning that using the estimated variances as if they were the known true variances can cause such problems. If you had the counts in the cells of the 2x2s, you could try a Bayesian approach. David Hoaglin On Thu, Feb 16, 2012 at 3:13 AM, Sofia Ramiro <sofiaramiro@hotmail.com> wrote: > > Dear all, > > I would like to ask your help for the following: I would like to perform a meta-analysis of some studies. However, I do not have the raw data to fill in the 2X2 table. I have a Relative Risk (and correspondent 95%CI) for each study. Is it possible to pool these RR and get a pooled estimate? If yes, how? > I have been searching online for this information, but haven't been successful... * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/

**References**:**st: Meta-analysis pooling relative risk from relative risks possible?***From:*Sofia Ramiro <sofiaramiro@hotmail.com>

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