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RE: st: Meta analysis of studies with varying duration of follow-up


From   "Tiago V. Pereira" <tiago.pereira@mbe.bio.br>
To   statalist@hsphsun2.harvard.edu
Subject   RE: st: Meta analysis of studies with varying duration of follow-up
Date   Thu, 17 Jun 2010 16:01:06 +0300 (BRT)

In practice, you can fit a random-effects meta-regression using -metareg-
to see in what extent the length of follow-up affects the observed
statistical heterogeneity. The effect size will be the dependent variable,
whereas the length of follow-up will be the study-level covariate. Make it
sure that you will be using the new version of -metareg-

Detailed information are found here:

http://www.stata-journal.com/article.html?article=sbe23_1

Cheers!

Tiago

--------------------------------
 Hi,  I am working on a meta analysis of randomized trials for an outcome
(categorical) for treatment vs. controls, but the studies all have
varying lengths of follow up.  The length of follow up between the
treatment and controls is the same but differs between studies.  What
would be a good approach to consider when pooling such data?  I
considered using hazard ratios, but the issue is there are very few
studies which report that.  Do you think using person years (no of
patients x follow-up in years) and weighting the studies based on this
would be reasonable approach?
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