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st: pkcross: crossover study simulation question


From   Michael McCulloch <mm@pinestreetfoundation.org>
To   Statalist Statalist <statalist@hsphsun2.harvard.edu>
Subject   st: pkcross: crossover study simulation question
Date   Sun, 21 Feb 2010 16:53:12 -0800

Dear Statalist friends,
I'm simulating a study which I originally thought was an AB-BA crossover design, but the more I contemplate the analysis, the more it seems I have a three-treatment design. The study calendar is as follows:

4 week washout > randomize to A or B >  4 week washout > switch A & B

During the washout period, patients receive "standard care".
I wish to compare:
	Standard care to A
	Standard care to B
	A to B

Would this then be analyzed as a series of 3 separate pkcross statements?




Best wishes,

Michael McCulloch
Pine Street Foundation
124 Pine Street
San Anselmo, CA 94960-2674
tel:	415-407-1357
fax: 	206-338-2391

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