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From |
Ricardo Ovaldia <ovaldia@yahoo.com> |

To |
statalist@hsphsun2.harvard.edu |

Subject |
RE: st: equivalence limit-thanks |

Date |
Sun, 16 Aug 2009 09:47:47 -0700 (PDT) |

Thank you very much Joseph. That is the information that I needed. Ricardo Ricardo Ovaldia, MS Statistician Oklahoma City, OK --- On Sun, 8/16/09, Joseph Coveney <jcoveney@bigplanet.com> wrote: > From: Joseph Coveney <jcoveney@bigplanet.com> > Subject: RE: st: equivalence limit > To: statalist@hsphsun2.harvard.edu > Date: Sunday, August 16, 2009, 10:49 AM > Ricardo Ovaldia wrote: > > I am still trying to figure how to do an equivalence test > in Stata. > All I have is a 2x2 table (Treatment x outcome). I can use > -cs- or -rdci- > to get the CI, but how do I compute the equivalence limit > assuming delta=25%, > for example? > > Also, can -pkequiv- be trick into doing this analysis? > > -------------------------------------------------------------------------------- > > If your delta is 25% for a risk difference (difference in > proportions), then you > can reject the null hypothesis of nonequivalence in favor > of the alternative > hypothesis of therapeutic equivalence if the confidence > interval (CI) from -cs- > (Wald) or -rdci- (various other methods) lies between -0.25 > and +0.25. > > For equivalence (as opposed to "noninferiority"), a 90% CI > is conventionally > used. This corresponds to a two, one-sided test > (TOST) method with alpha = > 0.05. > > So, set -level- at 90% for -cs- or -rdci- (whichever > command you choose), and if > the displayed CI is between the limits that you set for > equivalence (e.g., -0.25 > to +0.25, in your example), then you can declare > bioequivalence. > > Joseph Coveney > > > > * > * For searches and help try: > * http://www.stata.com/help.cgi?search > * http://www.stata.com/support/statalist/faq > * http://www.ats.ucla.edu/stat/stata/ > * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/

**References**:**RE: st: equivalence limit***From:*"Joseph Coveney" <jcoveney@bigplanet.com>

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