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st: misclassification cost term

From   Victor Mauricio Herrera <>
To   statalist <>
Subject   st: misclassification cost term
Date   Tue, 26 Feb 2008 21:11:44 -0600

I am interested in the identification of optimal cut points based on the minimization of the misclassification cost term [MCT = R*P*(1-SEN)+(1-P)*(1-SPE)], where P is the prevalence of the outcome, R is the ratio of the cost of a false negative to a false positive result, and SEN and SPE are the sensitivity and specificity of a continuous test at any possible cut point, respectively. Has anyone written a stata program to determine optimal cut points using this utility function and their confidence intervals based on, for instance, bootstrapping?


PhD., Student 
Population Health Sciences
University of Wisconsin
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Madison, WI 53726
(608) 265-3686
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