[Date Prev][Date Next][Thread Prev][Thread Next][Date index][Thread index]

From |
Richard Goldstein <richgold@ix.netcom.com> |

To |
statalist@hsphsun2.harvard.edu |

Subject |
Re: st: Number Needed to be Treated (NNT) |

Date |
Fri, 03 Aug 2007 12:55:21 -0400 |

This is an interesting and, to me, new definition of Number Needed to Harm (NNH) I use NNH quite differently as one over the difference in adverse event (side effect) rates and I think it is much more useful this way (e.g., one person can both improve and have a side effect -- or just one or, of course, neither. I would prefer to see the situation that Ronan is talking about as one where neither treatment is clearly better (from just the benefit side) Rich Goldstein Ronan Conroy wrote:

On 1 Aug 2007, at 13:55, Svend Juul wrote:NNT = 15.230769 (95% CI: 5.0701399; -15.169883) - the negative numbers meaning that exposure to x may prevent low birthweight.

The negative number has the interpretation of Number Needed to Harm (with its minus sign removed), just as a negative Attributable fraction is more usually written as "Prevented fraction in the exposed/population"

Thus the confidence interval in Svend's example runs from an NNT of 5 to an NNH of 15.

The other useful statistic that I recommend is the NTN (number treated needlessly). It is the NNT-1. So if you have to treat 400 people to prevent one event, then the number treated needlessly is 399. A salutary reflection for the average doctor.

P Before printing, think about the environment

=================================

Ronan Conroy

rconroy@rcsi.ie

Royal College of Surgeons in Ireland

120 St Stephen's Green, Dublin 2, Ireland

+353 (0)1 402 2431

+353 (0)87 799 97 95

* * For searches and help try: * http://www.stata.com/support/faqs/res/findit.html * http://www.stata.com/support/statalist/faq * http://www.ats.ucla.edu/stat/stata/

**References**:**Re: st: Number Needed to be Treated (NNT)***From:*"Svend Juul" <SJ@SOCI.AU.DK>

**Re: st: Number Needed to be Treated (NNT)***From:*Ronan Conroy <rconroy@rcsi.ie>

- Prev by Date:
**st: RE: Number Needed to be Treated (NNT)** - Next by Date:
**st: RE: RE: Question about cumulative density (cumul, xtile) -- quintiles and poverty status are not in sync. What am I doing wrong?** - Previous by thread:
**RE: st: Number Needed to be Treated (NNT)** - Next by thread:
**Re: st: RE: xtoverid error: internal reestimation of eqn differs from original** - Index(es):

© Copyright 1996–2015 StataCorp LP | Terms of use | Privacy | Contact us | What's new | Site index |