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Re: st: dose-response


From   "Svend Juul" <SJ@SOCI.AU.DK>
To   <statalist@hsphsun2.harvard.edu>
Subject   Re: st: dose-response
Date   Sun, 18 Mar 2007 21:56:07 +0100

Ali wrote:
 
Could anyone tell me what is the best way to test a dose response relationship
between a binary outcome measure and a four categories exposure. Is there any
method to test dose-response relationship following a binomial regression?
--------------------------------------------------------------
 
What is best depends....
 
To help yourself, start asking:
    findit dose response
 
It does not give much, but then try:
   findit trend test
 
Among the hits are this FAQ, which you should read.
 
FAQ     . . . . . . . . . . . . . .  A comparison of different tests for trend
        . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . W. Sribney
        3/96    Does Stata provide a test for trend?
                http://www.stata.com/support/faqs/stat/trend.html
 
Apart from what is mentioned in that FAQ, you can use -tabodds- (even for
stratified analyses; the above FAQ did not mention that). Also, a nonparametric
test like -kwallis- may be useful.
 
In a regression analysis with binary outcome, e.g. -logistic- and -binreg- you
may include your four-category exposure variable "as is".
 
Finally, you might want to study Roger Newson's -somersd- package. Find and
install it by -findit somersd-.
 
But what is best depends...
 
Hope this helps
Svend
 
________________________________________________________ 
 
Svend Juul
Institut for Folkesundhed, Afdeling for Epidemiologi
(Institute of Public Health, Department of Epidemiology)
Vennelyst Boulevard 6 
DK-8000 Aarhus C,  Denmark 
Phone, work:  +45 8942 6090 
Phone, home:  +45 8693 7796 
Fax:          +45 8613 1580 
E-mail:       sj@soci.au.dk 
_________________________________________________________ 

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