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st: mice experiment, risk for a clinical manifestation


From   Yoshiro Nagao <dengue_aedes@yahoo.co.jp>
To   statalist@hsphsun2.harvard.edu
Subject   st: mice experiment, risk for a clinical manifestation
Date   Wed, 7 Jun 2006 16:33:21 +0900 (JST)

Dear all,

I am asked by my friend for suggestion about
analysis of mice data. However, since
I am totally  lay in this field,
I have to ask for your suggestions...

Mice are inoculated by pathogens
to see the relationship  between
their immune responses 
and whether they manifest as a severe
complication of illness, named "Y".

However, many of the mice (say, 50%)
died from another irrelevant
form of illness "Z", before they
manifest "Y".
("Y" is relatively rare event, while
"Z" is more common)

My friend wants to see the contribution
of the age and immune responses
to the probability of "Y".

What study design is adequate?

Thank you very much for your assistance,
in advance.

Yoshiro Nagao

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