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RE: st: calculating stratum-specific likelihood ratios


From   "Moran, John (NWAHS)" <John.Moran@nwahs.sa.gov.au>
To   <statalist@hsphsun2.harvard.edu>
Subject   RE: st: calculating stratum-specific likelihood ratios
Date   Mon, 28 Nov 2005 15:37:09 +1030

Perhaps the book by Margaret S Pepe:
" The Statistical Evaluation of Medical Tests for Classification and
Prediction  " (see Chapter 8) (http://www.stata.com/bookstore/pepe.html)

and 
the associated software (http://www.fhcrc.org/science/labs/pepe/book/),
especially "lrreg" (Diagnostic Likelihood Ratio regression)  may be of
help here

E-mail: john.moran@nwahs.sa.gov.au


-----Original Message-----
From: owner-statalist@hsphsun2.harvard.edu
[mailto:owner-statalist@hsphsun2.harvard.edu] On Behalf Of Mark Russo
Sent: Monday, 28 November 2005 3:14 PM
To: Garry Anderson
Subject: Re: st: calculating stratum-specific likelihood ratios

Thanks Garry.

The reference is:

Peirce JC, Cornell RG. Integrating stratum-specific likelihood
ratios with the analysis of ROC curves. Med Decis Making
1993;13:141-51.

My objective is to determine--through ROC curves and LR--a threshold
value among a continuous variable (age) that predicts a dicotomous
variable (increased mortality at 5-yr f/u).  By combining adjacent
strata with statistically indistinct SSLRs (i.e., those with
overlapping 95% confidence intervals), we hope to determine a
threshold value for age.

Mark

-- 
Mark J. Russo, MD, MS
Department of Surgery
New York-Presbyterian Hospital/Columbia
177 Fort Washington Ave, 7GS313
New York, New York 10032
Phone: 212-202-4997
Fax:   212-202-4997
mr2143@columbia.edu


Quoting Garry Anderson <g.anderson@unimelb.edu.au>:

> What is the reference for Peirce please?
>
>
> At 10:47 PM 27/11/2005 -0500, you wrote:
> >Is it possible to calculate stratum-specific likelihood ratios
> with
> >confidence intervals as described by Peirce using Stata.  Or
> could
> >anyone recommend a program to perform these calculations?
> >Thanks,
> >Mark
> >
> >--
> >Mark J. Russo, MD, MS
> >Department of Surgery
> >New York-Presbyterian Hospital/Columbia
> >177 Fort Washington Ave, 7GS313
> >New York, New York 10032
> >Phone: 212-202-4997
> >Fax:   212-202-4997
> >mr2143@columbia.edu
> >
> >
> >
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