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st: comparison of diagnostic procedures

Subject   st: comparison of diagnostic procedures
Date   Wed, 7 Sep 2005 14:15:40 +0300


i would like to ask you about the following problem:

i have one variable which represents if the patient has the disease (coding: 0-
1)--and this is standard.
Additionally i have 12 more variables which represents the outcome of 12 
different diagnostic procedures (coding: 0-1 for all of them).I want to find 
which is the best diagnostic procedure. I calculate the sensitivity and 
specificity and their confidence intervals for each of them. If the confidence 
interval for the sensitivity of one diagnostic procedure do not overlap the 
confidence interval for the Se of another diagnostic procedure then the 
difference is significant.
Is there any test to perform and give p_value? Is there a need to make a 
correction for multiple comparisons.?

I will appreciate it if somebody help me!
thanks a lot!

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