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Re: st: Tests for trends in RCT subgroups (-metan-, -meta-, other?)


From   Roger Harbord <roger.harbord@bristol.ac.uk>
To   statalist@hsphsun2.harvard.edu
Subject   Re: st: Tests for trends in RCT subgroups (-metan-, -meta-, other?)
Date   Sat, 11 Jun 2005 08:59:59 +0100

There's a Stata faq on tests for trend that is well worth reading:
<http://www.stata.com/support/faqs/stat/trend.html>

Not completely clear from your description of the problem but i doubt that meta-analysis commands are the way to go.

Roger.

--On 10 June 2005 15:45 +0100 Matthew Sydes <Matthew.Sydes@ctu.mrc.ac.uk> wrote:


[Using Stata 8; impending upgrade to Stata 9]


Good afternoon,

I am interested in performing tests of trend in ordered subgroups from a
single randomised controlled trial.  It is possible to use meta-analysis
commands for this purpose, pretending that each subgroup is a separate
trial.  I have investigated the -meta- and -metan- commands.  However,
their tests for heterogeneity only seem to deal in global tests rather
than tests for trends.

Like numbers-at-risk on KM plots, subgroup trend tests are an issue I
often wrangle with and find that I can solve only outside of Stata (albeit
somewhat unsatisfactorily and unloggable fashion).

Any help on how I may address this matter within Stata would be much
appreciated.

Kind regards,

Matt

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