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st: unpaired regression


From   "Wallace, John" <John_Wallace@affymetrix.com>
To   "'statalist@hsphsun2.harvard.edu'" <statalist@hsphsun2.harvard.edu>
Subject   st: unpaired regression
Date   Mon, 10 May 2004 17:48:06 -0700

I have two measures of batch performance on which I'd like to perform a regression.  The measurements are taken on separate samples from the batch, and typically look something like:

            Assay1 Assay2

Btch1    5400         

Btch1    5320         

Btch1    5670         

Btch1                0.900

Btch1                0.905

Btch1                0.898

Btch2    8600         

Btch2    7840         

Btch2    7550        

Btch2                0.962

Btch2                0.955

Btch2                0.943

...etc (on for multiple batches which show correlated measures for the two assays)

-collapse- ing them to batch averages and then performing the regression is one approach, but it doesn't take variance of the measures themselves into account in the regression.  Is there a system for performing this type of analysis?

 

Thanks,

John Wallace | Research Associate | Test Method Development

AFFYMETRIX, INC. | 3380 Central Expressway | Santa Clara, CA 95051 | Tel:  408-731-5574 | Fax:  408-481-0435

 




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