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Re: st: Meta analysis of diagnostic test?


From   Roger Harbord <Roger.Harbord@bristol.ac.uk>
To   statalist@hsphsun2.harvard.edu
Subject   Re: st: Meta analysis of diagnostic test?
Date   Mon, 02 Dec 2002 16:35:54 -0000

Deeks, J.W. (2001) 'Systematic reviews of evaluations of diagnostic and screening tests', in Egger, Davey Smith & Altman (eds) 'Systematic reviews in health care : Meta-analysis in context' (BMJ, London)

- and references therein (refs 4-7 look a good place to start - if you can't get access to this book let me know and I'll send you the citations).

I don't know of any specific programs, Stata or otherwise. The type of summary ROC curves used in Figs 14.3-14.5 of the above reference require the ability to plot symbols (e.g. squares) of size specified by a variable - this doesn't appear to be something you can do with -graph-, only with by getting down to -gph- level (someone please correct me if i'm wrong). The book has a chapter about meta-analysis in Stata but whether Jonathan Deeks used Stata for the analysis or graphs in this chapter I've no idea - personally I'd be quite tempted to use S-plus/R for graphs of this sort.

Hope this is of some help,

Roger.
----------------------------------------------------
Roger Harbord mailto:roger.harbord@bristol.ac.uk
Department of Social Medicine, University of Bristol



--On 30 November 2002 13:32 +0100 Jannik Helweg-Larsen <jhl@cphiv.dk> wrote:


I'm trying to get some sort of conclusion from more than 15 very
heterogenous PCR diagnostic studies.

Considered to do some sort of meta analysis- but I've been unable (by
findit) to locate any specific Stata programs for such analysis.

Any suggestions or references?. Would summary ROC be useful and has
anybody written ado for these?

Jannik Helweg-Larsen, MD
Copenhagen HIV programme


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